How to deal with parameters for whole-cell modelling
نویسندگان
چکیده
منابع مشابه
How to deal with parameters for whole-cell modelling.
Dynamical systems describing whole cells are on the verge of becoming a reality. But as models of reality, they are only useful if we have realistic parameters for the molecular reaction rates and cell physiological processes. There is currently no suitable framework to reliably estimate hundreds, let alone thousands, of reaction rate parameters. Here, we map out the relative weaknesses and pro...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2017
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2017.0237